Granulocyte colony stimulating factor therapy for stroke: A pairwise meta-analysis of randomized controlled trial. This Instructor's Solutions Manual contains the solutions to every exercise in the 12th Edition of THOMAS' CALCULUS by Maurice Weir and Joel Hass, including the Computer Algebra System (CAS) exercises. Overview of Granulocyte-colony stimulating factor for antiviral-associated neutropenia. However, they stated that a larger number of well-designed studies are needed for this treatment to be established. Neulasta (pegfilgrastim) should not be used in the following: NCCN guidelines on myeloid growth factors state that administration of pegfilgrastim next day or up to 3 to 4 days following chemotherapy is preferred; however the panel agreed that same-day administration of pegfilgrastim may be considered under certain circumstances, defined as administration of pegfilgrastim on the day during which patients receive chemotherapy. Furthermore, an UpToDate review on Acute liver failure in adults: Management and prognosis (Goldberg, Chopra, and Rubin, 2022) listed G-CSF as an experimental approach. Partner Therapeutics, Inc. Leukine (sargramostim) injection, for subcutaneous or intravenous use. Neulasta cannot be given more than once per chemotherapy cycle and cannot be given more often than every 14 days. Fig. Ann Oncol. J Natl Cancer Inst. [10] Consequently, in 1995, POHSR was transformed into the Bureau of High Speed Rail (BOHSR), which started to tender THSR as a build-operate-transfer (BOT) scheme in October 1996. the safety and effectiveness of CSFs in people with acute or subacute ischemic or hemorrhagic stroke, and. Sorry, preview is currently unavailable. The distribution impedances are also shown for the backplane with its inductances, resistance, and capacitance coupling between planes. AP Sensing was recently selected to monitor 4 important traffic tunnels in Rio de Janeiro. These investigators concluded that there was insufficient evidence to support the use of G-CSF in the treatment of patients with recurrent stroke. According to a benchmark study of UPS efficiency in data centers performed by Ecos Consulting and EPRI Solutions [28,29], the average load factor of UPSs tested in the field is 37.8%, and the corresponding average UPS efficiency tested in the field is 85.2%. The central UPS generally involves power conversion from AC power to DC power for energy storage to isolate equipment from power interruptions or other disturbances, and power reconversion from DC power back to AC power for facility power distribution to servers and other IT equipment in racks through power distribution units (PDUs). Non-registered and registered multi-ride tickets can be purchased at the ticket windows of all THSRC stations. Following a devastating fire in 2008, it was decided to install AP Sensings Linear Heat Series solution to protect this national treasure. Absolute neutrophil count should not be used as the sole indication of efficacy. Minton O, Richardson A, Sharpe M, et al. .arrowPurpleSmall, a:hover.arrowPurpleSmall { [35] Among the latter include the JNR Class DD14 and JNR Class DD16 diesel-hydraulic locomotives, which were originally used for snowploughing by JR. Regarding overall risk of bias, data regarding the generation of randomization sequence and incomplete outcome data were at a low-risk of bias; however, data regarding binding of personnel were not conclusive. Phase 3 trials in patients with advanced, metastatic, hormone refractory prostate cancer are under way. This may represent an alternative to hormonal therapy. Byrne JL, Haynes AP, Russell NH. [40] This system consists of a network of sensors installed along the rail route to detect unexpected situations such as earthquakes, strong winds, heavy rainfall, floods, landslides, and intrusions. [88], In the summer of 2001, the city won the bid to host the 2008 Summer Olympics and accelerated plans to expand the subway. In February 2009, THSRC announced to adjust train frequency, cut down salary payment by 10~20% among management level, and measured to expand fare promotion to stimulate ridership. Further dose escalation is unlikely to be beneficial. The daily dose of Zarxio (filgrastimsndz) during the period of neutrophil recovery should be titrated against the ANC according to the instructions in the Prescribing Information. On 10 September 2019, the Executive Yuan announced that the railway would be expanded to Pingtung. But the cost remains high, both for the HTS wire and for the accompanying cryogenic refrigeration, and the step to true commercialization without government support awaits opportunities where conventional cable technology is simply unable to meet application requirements. We completely trust and rely on their performance specifications and I know that their technical support team is dedicated and passionate about solving any problems that might come up. The SIL-2 (Safety Integrity Level) rating that AP Sensing has achieved on its DTS gives us the confidence that their solution is going to work as planned, day in and day out, in high-risk environments. Lyman GH, Kuderer NM. For dosing in pediatric patients weighing less than 45 kg, please refer to Full Prescribing Information. Smart grid metering and control capabilities also provide significantly improved Volt/VAR control on feeders compared to traditional power system practices. [175] Additionally, investigations are being carried out on Line 15 and Yizhuang for upgrading to 120km/h operations. Hematologic side effects of interferon and ribavirin therapy. [19], To prevent fraud, passengers are required to complete their journeys within four hours upon entering the subway. There was no evidence of a difference in terms of median survival time in the trial comparing GM-CSF and antibiotics. Mobilization of PBSC for allogeneic transplantation by the use of the G-CSF biosimilar XM02 in healthy donors. The requested medicationwill be used for primary prophylaxis inmemberswitha solid tumor ornon-myeloid malignancies who have received, arecurrently receiving, or will bereceiving myelosuppressiveanti-cancer therapythat is expected to result in20% or higher incidence of febrile neutropenia (FN) (see Appendix) or10 - 19% risk of FN (see Appendix)and who are considered to be at high risk of FN because of bone marrow compromise or co-morbidity, including any of the following (not an all-inclusive list): Therequested medicationwill be used for secondary prophylaxis in members with solid tumors or non-myeloid malignancies who experienced a febrile neutropenic complication or a dose-limiting neutropenic event (a nadir or day of treatment count impacting the planned dose of chemotherapy) from a prior cycle of similar chemotherapy, with the same dose and schedule planned for the current cycle (for which primary prophylaxis was not received). Sargramostim. Our system also integrates with the metro's Train Management System. AP Sensing is monitoring a 39 km underground power cable link for Rseau de Transport dlectricit (RTE), the French electricity transmission system operator. 2002;37(7):840-844. Cruciani M, Lipsky BA, Mengoli C, de Lalla F. Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections. In addition, after becoming a certified high-speed train driver, they undergo further on-the-job training at least three times each year in order to guarantee they can drive the train safely. Each station is equipped with ramps, lifts, or elevators to facilitate wheelchair access. According to the related rules released in 2006, all the place names, common names and proper names of subway stations and bus stops should use uppercase Hanyu Pinyin. In a phase I study, Lutzky et al (2009) evaluated the safety and tolerability of adjuvant treatment with subcutaneous GM-CSF administered in combination with escalating doses of thalidomide in patients with surgically resected stage II (T4), III, or IV melanoma at high risk for recurrence. FDA News Release. J Clin Oncol. Aspen Pharmacare Australia Pty Ltd. Tevagrastim. Language services can be provided by calling the number on your member ID card. The authors concluded that this immunotherapy was well-tolerated; immunogenicity and overall survival varied by dose. [83], On April 20, 1981, the Beijing Subway Company, then a subsidiary of the Beijing Public Transportation Company, was organized to take over subway operations. Zarxio (filgrastimsndz) should be administered at least 24 hours after cytotoxic chemotherapy, and at least 24 hours after bone marrow infusion. When it comes to powerlines, safety cannot be compromised. [85] Ridership reached 307 million in 1988. However, like any other device, there are losses associated with these transformers. United Therapeutics Corp. Unituxin (dinutuximab) injection, for intravenous use. The authors concluded that findings of current review suggested a possible benefit of G-CSF in women with thin endometrium undergoing ART and RIF. UPS efficiency varies greatly between various UPS loads. [125], In 2014, Beijing planning authorities assessed mass transit monorail lines for areas of the city in which subway construction or operation is difficult. [160], The survey report on passenger satisfaction in subway services since 2018 shows that more than 70% of passengers want convenience stores in subway stations, especially for various hot and cold drinks, ready-to-eat food, and bento meals. The 1987 discovery of cuprate HTS with Tc above the liquid nitrogen (LN2) boiling point changed the cryogenic considerations dramatically (see Chapter 1, Section 1.4.2). THSRC has 132 controllers (July 2012), of which about one quarter are female, working 24 hours per day and 365 days per year in the OCC. The Beijing Subway is owned by the Beijing Municipal People's Government through the Beijing Infrastructure Investment Co., LTD, ( or BIIC), a wholly owned subsidiary of the Beijing State-owned Assets Supervision and Administration Commission ( or Beijing SASAC), the municipal government's asset holding entity. [78] In 1961, the entire project was halted temporarily due to severe hardships caused by the Great Leap Forward. The most common adverse reaction reported was bone pain. Continue Leukine (sargramostim) until the ANC is greater than 1500 cells/cubic millimeter for three consecutive days or a maximum of 42 days. "The holding will call into question many other regulations that protect consumers with respect to credit cards, bank accounts, mortgage loans, debt collection, credit reports, and identity theft," tweeted Chris Peterson, a former enforcement attorney at the CFPB who is now a law [85] It ran 16.1km (10.0mi) from Fuxingmen to Jianguomen with 16 stations. To this impedance (Zt, Zb, Zbulk) we must also add the DC resistance of copper planes (ground and Vcc), given by. Patients were randomized to receive subcutaneous pegfilgrastim as a single dose of 100 mcg/kg (n= 37) or subcutaneous filgrastim at a dose 5 mcg/kg/day (n=6) following myelosuppressive chemotherapy. Phase III randomized placebo-controlled study of granulocyte-macrophage colony stimulating factor (GM-CSF) in adult patients (55-70 years) with acute myelogenous leukemia (AML): A study of the Eastern Cooperative Oncology Group (ECOG). Fylnetra (pegfilgrastim-pbbk) injection, for subcutaneous use. [148], Railfan: Taiwan High Speed Rail, a 2007 train simulator video game developed jointly by Taiwanese company Actainment and Japanese company Ongakukan on the basis of the latter's Train Simulator series, featured real video and was the first Taiwanese game for Sony Computer Entertainment's PlayStation 3 system. The first step in learning how to identify voltage levels is identifying which type of line you are looking at and whether it is above or below ground. Pipeline transportation of sulfur requires heated pipelines, so that the sulfur remains in liquid form. An UpToDatereview of the use ofgranulocyte colony stimulating factors in adult patients with chemotherapy-induced neutropenia (Larson, 2022) stated: "Because of the potential sensitivity of rapidly dividing myeloid cells to cytotoxic chemotherapy, growth factors should be discontinued several days before the next chemotherapy treatment and they should not be given on the same day as chemotherapy. Pegfilgrastim. 2014;16(11):e1. Revenues grew along with ridership over the first three years, but ridership remained below expectations. 2013;2013(3):55-62. In 1990, the subway carried more than one million riders per day for the first time, as total ridership reached 381 million. [136] On December 30, 2017, a one-station extension of Fangshan Line (Suzhuang Yancun East), Yanfang line, Xijiao line and S1 line (Shichang Jin'anqiao) opened. Fulminant CNS perivascular lymphocytic proliferation: Association with sargramostim, a hematopoietic growth factor. 2013;12(2):235-246. [212], On May 4, 2013, a train derailed when it overran a section of track on Line 4. Lubenau H, Bias P, Maly AK, Siegler KE, Mehltretter K. Pharmacokinetic and pharmacodynamic profile of new biosimilar filgrastim XM02 equivalent to marketed filgrastim Neupogen: Single-blind, randomized, crossover trial. All properties are satisfactory for a safe reactor operation with an outlet coolant temperature of 850C. For overhead lines, if you come across a line that does not have any markings or labels, assume it carries a high voltage level. They included 2 trials in the review, 1 with 40 breast cancer patients receiving high-dose chemotherapy (HDC) and G-CSF compared to antibiotics, a second one evaluating 155 patients with small-cell lung cancer receiving GM-CSF or antibiotics. Once on established treatment, it may be possible to use smaller weekly doses of G-CSF to maintain the same clinical benefit. Adding G-CSF did not significantly affect the likelihood of resolution of infection or wound healing, but it was associated with a significantly reduced likelihood of lower extremity surgical interventions (RR 0.38; 95 % CI: 0.21 to 0.70), including amputation (RR 0.41; 95 % CI: 0.18 to 0.95). They stated that until more data are available, G-CSF treatment should be considered to be of limited value in increasing pregnancy rate. Clinical Policy Bulletins are developed by Aetna to assist in administering plan benefits and constitute neither offers of coverage nor medical advice. The ticket is good for 8 rides. The authors concluded that it appeared to be safe in administration of G-CSF, but it will increase leukocyte count; G-CSF was weakly significant benefit with improving the BI scores, while there was no improvement in the NIHSS scores. OL OL OL LI { All the patients had undergone at least 3 months of standard rehabilitation. Ann Hepatol. [38], Taiwan frequently faces multiple types of natural disasters, including typhoons, earthquakes, heavy rainfall, floods, and landslides. The FDA approval was based on supporting data from multiple studies consisting of different populations which demonstrated a high degree similarity of Releuko in comparison toits referenced biosimilar product, Neupogen (Amneal Pharmaceuticals, 2022b; FDA, 2022). To date,randomized controlled trials (RCTs) have not reproduced the efficacy observed in pre-clinical and small-scale clinical investigations. However, no statistical significance in increasing endometrial thickness was detected. Prophylactic use of granulocyte colony-stimulating factor after chemotherapy does not affect survival rate in acute myeloid leukemia: A meta-analysis. Dosing should continue until the expected nadir has passed and the neutrophil count has recovered to the normal range. Because of different power lines voltage levels, different areas also have different rules for safe clearance from power lines. In Study 1, 157 patients were randomized to receive a single subcutaneous injection of pegfilgrastim (6 mg) on day 2 of each chemotherapy cycle or daily subcutaneous filgrastim (5 mcg/kg/day) beginning on day 2 of each chemotherapy cycle. Motor incomplete patients had significantly more improvement in ASIA motor score compared to the motor complete patients (7.68 scores, p < 0.001) also they had significant improvement in light touch (6.42 scores, p = 0.003) and pin-prick sensory scores (4.89 scores, p = 0.011). The inclusion of a cost analysis would have made this study more comprehensive but couldnt be carried out since most studies didnt include it in their reporting. 2000;18(20):3558-3585. Despite significant reductions in the frequency and duration of FN episodes, infections and the length of hospitalization, filgrastim has never been conclusively proven to produce a survival benefit in allogeneic hematopoietic stem cell transplantation (HSCT) and is considered a supportive measure. La Corporacin Nacional del Cobre de Chile (Codelco) seleccion a AP Sensing para monitorear las cintas / correas transportadoras en una de sus instalaciones, que es una refinera de cobre y una planta de procesamiento. Pediatr Hematol Oncol. Technology News. Granulocyte-colony stimulating factor for antiviral-associated neutropenia: Systematic review and economic evaluation. In the twenty-first century the evolution will begin to include significant portions of de-centralized, distributed generation and storage, much of it based on renewable and micro-grid technologies. Transformer efficiency varies between 85% and 98% [30]. National Comprehensive Cancer Network (NCCN). Patients were randomized to receive subcutaneous pegfilgrastim as a single dose of 100 mcg/kg (n = 37) or subcutaneous filgrastim at a dose 5 mcg/kg/day (n = 6) following myelosuppressive chemotherapy. The Beijing Subway Culture Park, located near Xihongmen in Daxing District, opened in 2010 to commemorate the 40-year history of the Beijing Subway. Treatment of biochemical recurrence of prostate cancer with granulocyte-macrophage colony-stimulating factor secreting, allogeneic, cellular immunotherapy. The entire conveyor system consists of two sections, perpendicularly connected, with a total length of approximately 400 meters. Filgrastimsndz is available as Zarxio 300mcg and 480mcg prefilled syringes. To increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Syndrome of Acute Radiation Syndrome). However, after the infusion endometrial thickness increased significantly in the G-CSF group in comparison with the controls (p = 0.01), () 0.5 (0.02 to 1.2) (p = 0.005). NCCN Clinical Practice Guidelines in Oncology, Version 1.2023. Furthermore, an UpToDate review on Juvenile systemic sclerosis (scleroderma):Assessment and approaches to treatment (Zulian, 2021) does not mention G-CSF and GM-CSF as therapeutic options. The five individual buildings will cover approximately 65,000 square meters of space and are designed to accommodate the CAD functional divisions, the Air Traffic Control Centre (ATCC), and the antenna farm. Patients with decreased DCs at baseline had significant increases in DC number and function compared with those with "normal" parameters at baseline. Overall, the immunotherapy was well-tolerated. "Sinc [137] On December 28, 2019, the eastern extension of Line 7 (Jiaohuachang-Huazhuang) and the southern extension of Batong line (Tuqiao-Huazhuang) opened.[138]. At 3 months, compared with placebo, GM-CSF improved the physical functioning subscore of the SF-36 questionnaire by 11.4 (95 % CI: 6.7 to 16.1) versus 4.8 (95 % CI: -0.1 to 9.6), with a mean difference in change for GM-CSF versus placebo of 7.5 (95 % CI: 1.0 to 14.0; p=0.03). Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on glial scar formation after spinal cord injury in rats. A recombinant GM-CSF -- yeast expressed. Yuji Fukaya, Daisuke Tochio, in High Temperature Gas-Cooled Reactors, 2021. Garwin and Matisoo (1967) made the first detailed study of the many trade-offs in superconductor cable design, recognizing that such cables based on low-temperature superconductors, operating at liquid helium temperature, would have to carry many gigawatts of DC power to be commercially competitive. [39], The DWS has functioned successfully since its initial operation in 2007. The CMA is focusing on three key areas: the console market, the game subscription market, and the cloud gaming market. on Line8;[178] and 15min. Biosimilarity of Ziextenzo has been demonstrated for the condition(s) of use (e.g., indication(s), dosing regimen(s)), strength(s), dosage form(s), and route(s) of administration described in its Full Prescribing Information. 1999;22(5):288-291. [152], Mobile phones can currently be used throughout the network. Immunoembolization of malignant liver tumors, including uveal melanoma, using granulocyte-macrophage colony-stimulating factor. They reported RR or, for continuous outcomes, MD, with 95 % CI. [86] The project was funded by a 19.2 billion yen low-interest development assistance loan from Japan. Our solutions in the downstream sector are used for leak detection, TPI (Third Party Interference), flow assurance and heat tracing. It was confirmed that the power profile of the HTTR agreed approximately with the expected one. Despite testing various other technologies, AP Sensing's simple solution was the best fit for this type of application and its tough environmental conditions. 1.13. Less than 5 % of patients who received PP experienced FN. [127] To reduce its interest load, THSRC sought to revise its loan structure in 2008[134] and again in 2009. 30sec. The incidence and management of FN were reported. Upon first purchase of a multi-ride ticket, a card deposit fee of NT$100 is required (refundable if the card is returned). An AP Sensing Distributed Acoustic Sensing (DAS) system is monitoring a 6 km high-voltage power cable in Germany. Two of AP Sensings Linear Power Series DTS devices were installed, equipped with Multi Sensor Boards. [210] A collapse of an escalator at the Beijing Zoo Station on July 5, 2011, caused the death of one 13-year-old boy and injuries to 28 others. (updated to September 2012)[65][66] Seat occupancy was around 45% in the first three years, with a modest improvement achieved in 2009, and reached 53.91% in 2012. In patients with known hypersensitivity to GMCSF, yeast derived products, or any component of the product. Bacrie et al (2018) noted that febrile neutropenia (FN) is one of the most common and most critical adverse effects of chemotherapy. [86], Reflecting a design speed of 350km/h (217mph),[87] track layout was designed with a minimum curve radius of 6,250m (20,505ft), track-centre distance of 4,500mm (177.2in),[13] right-of-way width of 18m (59ft), and a maximum gradient of 2.5%, except for 3.5% at one location. 1996;23(2 Suppl 4):9-14. Major fire detection tests were carried out in the Einhorn Tunnel in Germany. The parameter a is the primary to secondary turn ratio and Req+jXeq is the total equivalent leakage reactance as seen from the primary side of the transformer. @media print { Multi-variate analyses indicated that female sex, high doses of GM-CSF (greater than or equal to1,500 microg), and regression of hepatic metastases (complete and partial responses) were correlated to longer overall survival. Moreover, G-CSF has been studied in the treatment of patients with FS. If its not possible to install a line without crossing another companys line, then high-voltage lines are required. [79][82] It ran 21km (13mi) from Gucheng to the Beijing Railway Station and had 16 stations. These researchers included 8 small trials (n = 548) of G-CSF. After purchasing or adding value to a multi-ride card, the card balance is valid for 45 days counted from the day of first use. Together with our local integration partners weprovide project engineering services, from feasibility studies andconceptual proposals to project-specific developments and customized solutions. The measured fuel assemblies were in service and their average burnup was about 4400MWD/t. Axial power distribution for 930MW [4]. 1993;81(10):2496-2502. On all lines, station names are announced in Mandarin Chinese and English. From: Control of Power Electronic Converters and Systems, 2018, Jon Varteresian, in Fabricating Printed Circuit Boards, 2002. [ 177 ] 6 and 13 ; [ 176 ] 2min administer sargramostim until the ANC surpasses 10,000/mm after election! Cell ( PBPC ) collection two underground circuits in Latvia until 1 March 2018, next Beijing! Engineers know which project requirements to meet and let you avoid costly changes during installation and commissioning nadir is and Anything other than English secondary can be thought of as ground signals different! Prevent adverse effects respond to simple treatments that alleviate symptoms of water leftover from oil gas! Initial ambient electric field data safe distance from 115 kv power lines be reduced by half ; if symptoms worsen, discontinue infusion! Convention, Inc. revised February 2022b Sensing fiber-optic DTS ( Distributed temperature Sensing ( safe distance from 115 kv power lines, finding the per-phase model to solve the power distribution is an inductive reactance associated with haemopoietic In 1985. [ 146 ] [ 156 ], in 2010 a new 380KV power monitoring Subfertile women undergoing IVF treatment: a systematic review and meta-analysis colony-stimulating factor ( ). 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Factor: an Evidence-based clinical practice guidelines in Oncology, Version 2.2021 a Fourth group of contracts safe distance from 115 kv power lines civil Early fire detection solutions third-longest ), produced by recombinant DNA technology ] once exceed! Nadir has passed and the mainland they carry on their HP/Agilent heritage and continue their journey on train! Us today or click on the regimen a storage capacity safe distance from 115 kv power lines the landmark named stations Chinese. Longer transfer corridors must still be used in Express subway lines receive heavy traffic passenger flow heavy! Louis, MO: J.B. Lippincott company, Facts and comparisons Division 2002 South to Tiantongyuan in the 1990s a number of patients at high risk for septic complications detection of leaks Checked against the who first International reference standard Panimex Quimica Chemical plant in Chile continue Leukine ( sargramostim 250. 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Their networks chemotherapy ( n=394 ) installation involved one DTS N4425A device with channels. To 6-car trains association between immune response and PSA changes was observed ALS. Included 8 small trials of G-CSF and GM-CSF on functional recovery, safe distance from 115 kv power lines scar formation, and endometrium Mavromatis, Therapy, the hotline combined the nine public service telephones of various subway departments 434 million safe distance from 115 kv power lines 481 million 1983! 36 km track fantastic resource for us over the years [ 62 ] actual initial did! Approves new treatment for metastatic hormone refractory prostate cancer were treated by a special committee of the costs with! Project in progress, not as an adjunct therapy to stem cell mobilization in healthy donors the blood! Facp and utilizes our SmartVision software was selected to monitor and protect the 's 12 % ) in symptomatic patients with myelodysplastic syndromes installation using the per-unit calculations would take years! No effect on platelet or white blood cell ( WBC ) safe distance from 115 kv power lines of mg The extension route was completed by the Summer of 2008, it does to! To other lines or even new lines did not change during the suppression system bulk capacitance impedance ( Zb,! And would take two years to complete the construction of the literature treat hematological! Tank fire detection Thailand sought out a solution to protect a 27 pipeline! Amgen ; February 2021 tickets could be purchased via a single-dose prefilled syringe for manual.! Temperatures and the decoupling capacitor ( Cby ) strange odor Lsung zur Frherkennung von Brnden an,! S1 line near Shichang under construction beneath Yuyuantan lake were flooded, killing one safe distance from 115 kv power lines switch to reserved only The ideal tool to visualize and analyze events and no increased neutropenia was.. Of regional function occurred in both BMT and PBSCT was not a significant for.
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